With that being said, using isotretinoin early on in the development of severe acne may lessen scarring, both emotional and physical, and relapse later in life may be less damaging than hard-to-clear scarring. This is not to suggest that young patients should avoid Accutane - just that they should be aware that they are at risk of a higher relapse rate. This is likely due to the fact that older patients generally experience fewer changes and shifts in hormones as they age, while younger patients have many years of hormonal changes before them. There is increasing evidence that younger patients relapse more readily than older ones. Younger Patients May Relapse More Readily
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So if you took Accutane and your skin cleared up, but then you still get regular pimples afterward - don't panic - it's probably just something in your diet or lifestyle that needs to be tweaked. Some patients will not accept even minimal disease however, this speaks more to a patient's own reservations, and not necessarily the efficacy of the product. This means that people with severe acne who used Accutane wouldn't consider the development of a few pimples after treatment to be a relapse, whereas people with mild acne who used Accutane would. These cases respond extremely well, and then patients expect to remain clear, whereas the initial cohorts of patients had severe disease and were less concerned by the resurgence of a few spots. One explanation might be due to the fact that isotretinoin is now used to treat patients with less severe acne. Here are 8 reasons that you may relapse after Accutane: 1. It's Being Used On Less Severe Cases However, recent clinical experience suggests that the long-term cure rate may be lower than was initially thought, and Accutane relapse rates may be higher, depending on a variety of variables ( 1)( 2)( 3)( 4).įor some, it may be a permanent cure to acne, but acne can come back after Accutane for 10% and 60% of patients.
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Most patients who receive oral isotretinoin or Accutane will be free of acne by the end of 4–6 months of treatment depending on the dose. For example, here's some before and afters of Accutane:Ī post shared by Kali | acne positivity on at 8:19am PDT This is why people opt for it - it's almost a sure thing. To date, the efficacy of isotretinoin has not been superseded by any other treatment, and over two decades later isotretinoin remains the most clinically effective anti-acne therapy, producing long-term remission and/or significant improvement in many patients. Anywhere from 10% to 60% of patients may experience acne again in the future. Accutane however is not always a permanent cure for acne. Regardless of the stigma surrounding it, Isotretinoin remains the most effective treatment for severe acne, as well as cases of more moderate acne that is unresponsive to other treatment modalities. Thankfully, isotretinoin is considered safe. People are worried that they're going to cause serious damage to their bodies by using it, even though side effects like that are very rare. This is often people's last resort, not only because doctors aren't "supposed" to prescribe it as a first-line treatment (they would rather jump right to harmful antibiotics), but also because there is a lot of fear-mongering surrounding it as a treatment.
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Whether the patient is able to metabolize Accutane well.Whether or not the patient was on anti androgen treatment.Dosage size of Accutane and length of the treatment.What food or drink Accutane was taken with.The factors that determine if you will relapse after Accutane: In a 2021 study, patients had a 69.5% relapse rate 2 years after their isotretinoin ( accutane ) course. Yes, The relapse rate for Accutane can be as low as 10% to as high as 60% depending on dosage and length of treatment. But can acne come back after accutane? The unfortunate answer is yes, some people will have a relapse after taking Accutane and the long term cure rate is actually a lot lower than what people expect. Most patients are free of acne after 4 to 6 months of treatment.
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When under the care of your dermatologist or doctor, Isotretinoin or Accutane is mostly considered safe and one of the most effective treatments for severe acne.